⚫️Somatostatin
🟣 مكان الافراز؟
D cells in GIT mucosa ➡️ 65%
Delta cells of pancreatic islets ➡️ 35%
🔶️ ايه المحفز؟
انه وجود عند الخلايا Glucose and amino acids
أو لو فى احماض عند antrum أو Deudenum
🛑 طب بيعمل ايه؟
ده هرمون مخنوق من حياته مش طايق حد
بيعمل inhibition لكل حاجه
1️⃣ inhibit secretion of gastrin , CCK , VIP , GIP secretin and motilin
2️⃣ inhibit endocrine and exocrine pancreatic secretion
3️⃣ inhibit gastrin motility and acid-induced gastrin secretion
4️⃣ inhibit contraction of Gall Bladder and absorption of glucose , amino acids and TAG
🟣 مكان الافراز؟
D cells in GIT mucosa ➡️ 65%
Delta cells of pancreatic islets ➡️ 35%
🔶️ ايه المحفز؟
انه وجود عند الخلايا Glucose and amino acids
أو لو فى احماض عند antrum أو Deudenum
🛑 طب بيعمل ايه؟
ده هرمون مخنوق من حياته مش طايق حد
بيعمل inhibition لكل حاجه
1️⃣ inhibit secretion of gastrin , CCK , VIP , GIP secretin and motilin
2️⃣ inhibit endocrine and exocrine pancreatic secretion
3️⃣ inhibit gastrin motility and acid-induced gastrin secretion
4️⃣ inhibit contraction of Gall Bladder and absorption of glucose , amino acids and TAG
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