60% of marital unions in people of Pakistani heritage in Bradford are first cousins. These account for a third of birth defects. The disturbing risks of 'extreme inbreeding' revealed, despite NHS claims it's no more dangerous than being an older parent.
https://www.dailymail.co.uk/health/article-14173033/risks-inbreeding-marrying-cousin-genetic-conditions.html

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We moved to Bradford when we were expecting our 3rd child. My wife was confused to say the least when at her pre-natal checks they repeatedly asked if she was related to me in any other way than by marriage.